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ORYNOCOAT E 100 / EPO

The perfect blend of art and science in coating materials
ORYNOCOAT® E 100/EPO is a functional polymer coating system formulated for rapid drug release in acidic conditions. It is soluble below pH 5.0, making it suitable for targeting release in the stomach and upper gastrointestinal tract.
  • Acidic pH Solubility Specifically designed for solubility in gastric fluids (below pH 5.0).
  • Immediate Release Rapid disintegration and release in low pH environments.
  • Functional Coating Offers protection of pH-sensitive actives until they reach the desired location.
  • Versatile Application Available in both powder and granule form for various process setups.
Application in products
Pharmaceutical Tablets
  • Immediate-release tablets
  • Sustained-release tablets
Technical specifications 
  • Appearance: White or slightly off-white powder or granules
  • Availability: Granules / Powder
  • Solubility: Soluble below pH 5.0
  • Polymer Type: Immediate-release, pH-dependent
  • USP/NF: Amino Methacrylate Copolymer
Safety and Toxicology
  • Non-toxic: Free of harmful organic solvents
  • Dermatological safety: Suitable for oral use with appropriate safety margin
Storage and Handling
  • Store in a cool, dry place (15°C–30°C), away from moisture and direct sunlight
  • Keep container tightly sealed when not in use
  • Stir thoroughly before application for uniform dispersion
Packaging and Retesting
  • 25 kg HDPE drums with light protection
  • Every 18 months for performance validation
Frequently Asked Questions

Your questions our answers.

How does Orynocoat work?
Orynocoat forms a protective film over tablets, controlling drug release and enhancing stability.
What are the key benefits of using Orynocoat?
It improves tablet stability, masks taste, ensures controlled release, and enhances patient compliance.
How is Orynocoat used in formulations?
It is applied as a film coating over tablets using a polymer dispersion technique.
What are the safety considerations for using Orynocoat?
It is non-toxic, safe for oral use, and complies with pharmaceutical safety standards.