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ORYNOCOAT S 100

The perfect blend of art and science in coating materials
ORYNOCOAT® S 100 is an enteric coating polymer that dissolves at pH 7.0 and above, making it ideal for delayed-release formulations targeting the distal intestine or colon. It offers strong acid resistance and predictable release profiles for drugs requiring late intestinal delivery.
  • Targeted Colonic Release Dissolves only at pH ≥ 7.0, enabling drug delivery to the ileum or colon.
  • Superior Acid Resistance Protects sensitive actives from degradation in the stomach and upper small intestine.
  • Stable Film Formation Produces robust, transparent films with high resistance to gastric fluids.
  • Regulatory Acceptance Conforms to USP/NF and Ph. Eur. standards for pharmaceutical coatings.
Application in products
Pharmaceutical Tablets
  • Immediate-release tablets
  • Sustained-release tablets
Technical specifications 
  • Appearance: White or off-white fine powder
  • Dissolution Profile: Dissolution above pH 7.0
  • Polymer Type: Enteric-release methacrylic acid copolymer
  • USP/NF: Methacrylic Acid and Methyl Methacrylate Copolymer (1:2)
  • Film Properties: Transparent, brittle if plasticizer is not used, strong gastric protection
Safety and Toxicology
  • Non-toxic: Complies with USP/NF and Ph. Eur. monographs
  • Dermatological safety: Non-toxic, non-irritant, and safe for oral delivery
Storage and Handling
  • Store in original container below 30°C
  • Protect from humidity, light, and heat
  • Use dry air during processing and dispersion
Packaging and Retesting
  • 25 kg HDPE drums or fiber drums with food-grade PE liner.
  • 18 months; batch should be retested before use if expired
Frequently Asked Questions

Your questions our answers.

How does Orynocoat work?
Orynocoat forms a protective film over tablets, controlling drug release and enhancing stability.
What are the key benefits of using Orynocoat?
It improves tablet stability, masks taste, ensures controlled release, and enhances patient compliance.
How is Orynocoat used in formulations?
It is applied as a film coating over tablets using a polymer dispersion technique.
What are the safety considerations for using Orynocoat?
It is non-toxic, safe for oral use, and complies with pharmaceutical safety standards.