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The PUREQUIMICA RANGE

COPOLYMER OF METHACRYLIC ACID AND DIVINYL BENZENE
PUREQUIMICA 4234

Features you can trust

Applications that make a difference
  • Tablets
  • Capsules
  • Effervescent tablets
  • Granules
The power of Ion exchange resin
  • Tablet Disintegrant Purequimica is a highly effective tablet disintegrant, thanks to its large swelling capacity in aqueous solutions. When hydrated, it enhances the forces between particles in the tablet, promoting rapid disintegration. This ensures quicker drug release and improved bioavailability. Purequimica is typically used at 1-10% of the total weight in solid dosage formulations, making it an ideal choice for efficient tablet disintegration. 
  • Adhesion The bonding of particles in compressed tablets must be overcome for a tablet to disintegrate, thereby releasing the drug for bioavailability. Some disintegrants are adhesive in nature and are thus ineffective in overcoming particle bonding. Purequimica, being nonadhesive, is frequently much more effective as a disintegrant in tablet formulations. 
  • Water Adsorption Purequimica adsorbs water rapidly due to its hydrophilic nature. Upon hydration, the resin particles swell, and when incorporated into the tablet, the swelling of Purequimica generates sufficient force to rupture and disintegrate even those tablets that have been subjected to very high compression forces during the tableting process. 
Frequently Asked Questions

Your questions our answers.

How does Purequimica work?
Purequimica disintegrates tablets by rapidly swelling when water is absorbed, generating enough force to break apart the tablet. Its nonadhesive and hydrophilic properties enhance disintegration and improve drug bioavailability.
What are the key benefits of using Purequimica?
Purequimica offers key benefits like rapid tablet disintegration through swelling, improved drug bioavailability, and reliable performance, complying with Polacrilin Potassium NF specifications for consistent results in oral dosage formulations.
How is Purequimica used in formulations?
Purequimica is used in tablet formulations through direct compression or wet/dry granulation. It enhances disintegration, improves drug dissolution, and increases bioavailability by utilizing its swelling and wicking properties.